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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL23
All Species:
19.39
Human Site:
S139
Identified Species:
35.56
UniProt:
Q16540
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16540
NP_066957.3
153
17781
S139
E
E
R
Q
Q
R
Q
S
S
D
P
R
R
G
G
Chimpanzee
Pan troglodytes
XP_508219
185
20823
S171
E
E
R
Q
Q
R
Q
S
S
D
P
R
R
G
G
Rhesus Macaque
Macaca mulatta
XP_001092196
153
17778
S139
E
E
R
R
Q
R
Q
S
S
D
P
R
R
G
G
Dog
Lupus familis
XP_540784
195
22748
T181
E
D
Q
R
R
R
Q
T
R
D
P
R
R
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O35972
146
17103
S133
L
P
Q
Q
R
Q
S
S
D
L
R
C
P
G
I
Rat
Rattus norvegicus
Q63750
146
17032
S133
L
P
Q
Q
R
Q
S
S
D
P
R
C
P
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517094
106
11828
A93
E
E
R
R
K
Q
K
A
D
P
R
W
G
G
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089781
153
18185
K139
E
N
E
K
Q
R
Q
K
N
D
P
R
R
G
G
Zebra Danio
Brachydanio rerio
Q6IQS9
153
18239
K139
E
D
E
R
Q
R
Q
K
P
D
P
R
R
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W021
150
17859
R137
G
F
R
R
F
L
D
R
N
K
K
R
P
G
T
Honey Bee
Apis mellifera
XP_001120599
144
17348
T131
E
E
N
F
R
K
F
T
K
N
N
K
C
P
G
Nematode Worm
Caenorhab. elegans
Q9GYS9
159
19076
L142
Q
E
E
L
K
D
K
L
N
E
R
Y
A
N
R
Sea Urchin
Strong. purpuratus
XP_792235
148
17360
K135
K
E
E
K
V
S
K
K
F
V
S
R
G
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
92.1
64
N.A.
83.6
84.9
N.A.
30.7
N.A.
65.3
61.4
N.A.
40.5
40.5
32.7
49
Protein Similarity:
100
82.1
96
72.3
N.A.
88.2
89.5
N.A.
47
N.A.
82.3
78.4
N.A.
56.2
60.7
53.4
65.3
P-Site Identity:
100
100
93.3
60
N.A.
20
20
N.A.
26.6
N.A.
66.6
66.6
N.A.
20
20
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
40
40
N.A.
60
N.A.
80
80
N.A.
33.3
53.3
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
16
8
0
0
% C
% Asp:
0
16
0
0
0
8
8
0
24
47
0
0
0
0
0
% D
% Glu:
62
54
31
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
8
0
8
8
0
8
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
16
85
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
8
0
0
16
16
8
24
24
8
8
8
8
0
0
0
% K
% Leu:
16
0
0
8
0
8
0
8
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
24
8
8
0
0
8
0
% N
% Pro:
0
16
0
0
0
0
0
0
8
16
47
0
24
8
0
% P
% Gln:
8
0
24
31
39
24
47
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
39
39
31
47
0
8
8
0
31
62
47
0
8
% R
% Ser:
0
0
0
0
0
8
16
39
24
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _